Research Engagement and ImpactImpact Seed Funding – supporting our Flinders ECRs - Dr Linlin Ma
![Gold nanoparticles and red blood cells travelling through an artery](/rp/Content/Images/2018-10/shutterstock_624720602-crop-resize.jpg)
Inspiring Research will be profiling recipients of the inaugural Flinders University Impact Seed Funding Grants – awarded July 2018.
Today we’re meeting Dr Linlin Ma, College of Medicine and Public Health, and highlighting aspects of her research project "Targeting hEAG1 channel with gold nanoparticles for diagnostic imaging and targeted treatment of colorectal cancer".
Linlin’s project aims to develop the potassium ion channel hEAG1 as a biomarker for gold nanoparticle -based diagnostic imaging and targeted chemotherapeutic treatment for Colorectal cancer (CRC). As CRC is well known for its very low chemotherapy success rate and acquired resistance, any new method of improving this success rate would be welcomed.
CRC is the third most frequently diagnosed malignancy and the fourth leading cause of cancer death worldwide. The global burden of CRC is expected to increase by 60% to more than 2.2 million new cases and 1.1 million deaths by 2030. It is particularly a problem in Australia/New Zealand, as we have the highest morbidity in the world. The current treatments rely on surgery and chemotherapy and are a considerable burden for patients physically, psychologically and economically.
Moreover, a rising incidence of CRC in younger individuals has opened an urgent need for non-invasive screening methods with improved accuracy to substitute the inaccurate stool test and the invasive colonoscopy. Nanoparticle-based technologies are considered a promising strategy with the potential to revolutionise cancer diagnosis and treatments. Impact Seed Grant funding will enable testing of the feasibility of the idea and generate solid preliminary data, and, in doing so, showcase the huge potential of the novel approach for further explorations for cancer treatment and survivability.
Linlin will be working with her research mentor Professor Ross McKinnon, College of Medicine and Public Health, who will provide expertise in molecular oncology and bring a broad knowledge of cancer research to the project. As the project is multidisciplinary, integrating the research fields of ion channel biology, nanotechnology, and molecular oncology, Linlin will also be collaborating with nanotechnology researchers Professor Joe Shapter and Associate Professor Ingo Koper, Flinders’ College of Science and Engineering.
Flinders University Impact Seed Funding Grants provide an opportunity for Early Career Researchers (ECRs) to develop their careers and enable key research projects or promotion of research outcomes. Flinders University has partnered with our community of donors to provide the opportunity for ECRs to receive financial support to develop and fortify their skill sets. Our supporters want to make a difference by building our researchers’ capacity and capabilities to make a positive impact. Please contact Dr Marina Delpin if you wish to know more about this initiative.
More posts in "Research Engagement and Impact" series:
- (13 Dec 2018) ECR Spotlight - Dr Ben Lewis
- (29 Nov 2018) Impact Seed Funding – supporting our Flinders ECRs – Dr David Smith
- (29 Nov 2018) Research Roundup - 29 November 2018
- (15 Nov 2018) Impact Seed Funding – supporting our Flinders ECRs – Dr Lua Perimal-Lewis
- (14 Nov 2018) Research Roundup - 15 November 2018
- (01 Nov 2018) Flinders research from an undergraduate class to a record breaking swim attempt
- (01 Nov 2018) Research Roundup - 1 November 2018
- (31 Oct 2018) ECR Spotlight - Dr Bev Rogers
- (31 Oct 2018) Flinders researchers trip to Germany on bringing science to market
- (18 Oct 2018) Melbourne and Canberra fellowships advance research and leadership skills for Flinders researcher
- (18 Oct 2018) Impact Seed Funding – supporting our Flinders ECRs - Dr Linlin Ma
- (18 Oct 2018) Research Roundup - 18 October 2018
- (04 Oct 2018) How can Australian innovation create new industries and jobs?
- (04 Oct 2018) Research Roundup - 4 October 2018
- (27 Sep 2018) Saving Nemo at Ngeringa Winery
- (20 Sep 2018) Assisting the UN and developing nations on how to measure wellbeing
- (20 Sep 2018) Equity Hub to assist translating research into change
- (06 Sep 2018) Steps to improve gender diversity in coastal geoscience and engineering
- (23 Aug 2018) Finding the invisible traces
- (09 Aug 2018) Diving in Deep to strengthen links with UNESCO members
- (09 Aug 2018) Impact Seed Funding – supporting our Flinders ECRs
- (09 Aug 2018) Older Adults engaging for a better quality of life
- (08 Aug 2018) The scientist’s guide to a successful career in academia
- (27 Jul 2018) Flinders aiming to lead the blueeconomy
- (27 Jul 2018) Can you have a conversation with a computer?
- (12 Jul 2018) Flinders linking with arts and culture to explore their real value
- (12 Jul 2018) WHO internship for Flinders researcher
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- (28 Jun 2018) Flinders’ led project top in Radiation Research
- (18 Jun 2018) Nothing going to waste - Flinders NIH Success
- (18 Jun 2018) ECR Spotlight - In Conversation with Dr Sam Elliott
- (29 May 2018) Flinders leading the reviews to improve remote health
- (17 May 2018) Generating conversation through The Conversation
- (15 May 2018) ECR Spotlight - Dr Ashok Manoharan 2018
- (03 May 2018) Flinders’ Archaeologist off to Cambridge for a year
- (26 Mar 2018) New chapter of Indigenous history told through food
- (08 Mar 2018) Flinders linking with Indigenous groups to explore aspects of colonial Australia
- (22 Feb 2018) ECR Spotlight - Ian Moffat
- (21 Feb 2018) Flinders working to Beat Cancer
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- (24 Jan 2018) ECR Spotlight - Alice Clement
- (21 Dec 2017) A Flinders first - automated launch and recovery for autonomous underwater vessels
- (13 Dec 2017) 2017 Vice-Chancellor's Award for Early Career Researchers
- (11 Dec 2017) ECR Spotlight - Vishnu KK Nair
- (06 Dec 2017) NHMRC success for Flinders
- (24 Nov 2017) Aiming to improve the health, education and wellbeing of children
- (17 Nov 2017) Accelerating the Interplay Wellbeing Framework
- (16 Nov 2017) 2018 Visiting International Research Fellows to Flinders
- (15 Nov 2017) ECR Spotlight - Ashokkumar Manoharan
- (15 Nov 2017) 2018 Flinders Endeavour Scholars and Fellows announced
- (14 Nov 2017) Time to Bragg about science writing
- (10 Nov 2017) Flinders Forensic Science cleans up at Awards
- (10 Nov 2017) Flinders successes in the recent ARC grant round
- (30 Oct 2017) Students Present Around the World
- (20 Oct 2017) Over $8 Million to Flinders from the National Palliative Care round
- (19 Oct 2017) ECR Spotlight - Sam Schultz
- (17 Oct 2017) Flinders' Fresh Scientists in the Pub
- (11 Oct 2017) Indigenous knowledge, not just for Indigenous communities
- (06 Oct 2017) Leading Drug and Alcohol researchers at Flinders’ NCETA secure $1.7 million in funding
- (05 Oct 2017) ECR Spotlight - Margaret Shanafield
- (28 Sep 2017) Our Distinguished Geographer
- (07 Sep 2017) ECR Spotlight - George Karpetis
- (01 Sep 2017) Eureka! Prize for blood test for bowel cancer recurrence
- (22 Aug 2017) Different environments, different DNA, different dolphins?
- (17 Aug 2017) ECR Spotlight - Dr Harriet Whiley
- (03 Aug 2017) ECR Spotlight - Giselle Rampersad
- (17 Jul 2017) Time to Scope your research - FAST
- (17 Jul 2017) Time to Scope your research - Hoverflies
- (13 Jul 2017) Tips from a first time interviewee
- (12 Jul 2017) Saving Nemo at the Star of Greece
- (07 Jul 2017) Invasion of the European crabs
- (20 Jun 2017) Fossil finds bring Australia's evolutionary history to life
- (07 Jun 2017) Peer Prize up for grabs
- (02 Jun 2017) Tracking the marine ecosystems in South Australia
- (29 May 2017) Be Your Best for Impact
- (18 May 2017) Aiming to catch criminals as never before
- (05 May 2017) Excavating with and in a Community
- (29 Apr 2017) What does engagement look like? Community-initiated research.
- (24 Apr 2017) Planning for one of the world’s youngest nations
- (07 Apr 2017) Pitching ON tasty seaweed jelly
- (29 Mar 2017) Best and Brightest for Hearts
- (27 Mar 2017) The Best Student Publications - Flinders 2016 edition
- (16 Mar 2017) From workshop to book - Underwater archaeology and 3D
- (21 Dec 2016) Recent Funding Success
- (21 Dec 2016) Research Impact - Point of Care Testing
- (21 Dec 2016) New ARC College of Experts
- (20 Dec 2016) Flinders Celebrates - 2016 Research Successes
- (19 Dec 2016) Vice-Chancellor Awards for Research Excellence
- (19 Dec 2016) Cardiology, Mental Health Projects among NHMRC Grant Success
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